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Published on: January 22, 2018
Inflammatory 68 Ga FAPI-46 Uptake Mimicking a Sister Mary Joseph's Nodule in a Case of Gastric Signet Ring Cell
Zehranur Tosunoğlu1, Mustafa Bozkurt2, Sibel Erdamar3
1Istanbul Training and Research Hospital, Clinic of Nuclear Medicine, University of Health Sciences.
Abstract:
Fibroblast activation protein (FAP) is a type II transmembrane protease expressed in cancer-associated fibroblasts (CAF) that constitute a part of the tumor stroma and influence the tumor microenvironment. Although FAP is not expected to be physiologically expressed in noncancer-associated cells, it can be observed in wound healing, arthritis, atherosclerotic plaques, and fibrosis. In this case, we would like to present early-stage 68 Ga FAPI-46 PET/CT inflammation findings at the trocar entry site mimicking the Sister Mary Joseph's nodule in a patient diagnosed with gastric signet ring cell carcinoma.

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