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Evaluating the Need for Pre-CoMiSS™, a Parent-Specific Cow's Milk-Related Symptom Score: A Qualitative Study
Yvan Vandenplas1, Kateřina Bajerová2, Christophe Dupont3
1KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium.
Nutrients
|May 14, 2025
Summary
A new tool, Pre-CoMiSS™, helps parents track infant symptoms of cow
Area of Science:
- Pediatrics
- Allergology
- Qualitative Research
Background:
- Cow's milk allergy (CMA) poses a significant health challenge.
- The Cow's Milk-related Symptom Score (CoMiSS™) aids healthcare professionals in CMA awareness.
- A parent-reported version, Pre-CoMiSS™, was explored for its utility.
Purpose of the Study:
- To assess the need for a parent-reported CMA screening tool (Pre-CoMiSS™).
- To explore the usefulness of Pre-CoMiSS™ for parents and primary care physicians (PCPs).
Main Methods:
- Qualitative study involving interviews with parents and PCPs across four European countries.
- Participants included parents of infants (2-12 months) and PCPs.
- Thematic analysis was used to derive findings from semi-structured interviews.
Main Results:
- Parents universally found Pre-CoMiSS™ easy to use and helpful for understanding infant symptoms and physician consultations.
- Physicians in the UK, Spain, and Sweden viewed Pre-CoMiSS™ favorably for improving symptom reporting.
- German physicians expressed mixed views, citing concerns about increased parental anxiety, overdiagnosis, and workload.
Conclusions:
- The Pre-CoMiSS™ tool was generally well-received by parents and most physicians.
- Concerns regarding parental anxiety and physician workload were noted, particularly in Germany.
- Further validation could establish Pre-CoMiSS™ as a valuable tool for parents and PCPs in managing potential CMA.

