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The microglial lineage: present and beyond
Wei-Wei Chen1, Zhisheng Wu1, Hanjie Li2
1Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Trends in Immunology
|May 14, 2025
Abstract:
Emerging studies demonstrate the presence of cells with microglial features in peripheral tissues. Here, we propose using the term 'microglial lineage' to categorize both these cells and classical microglia. Microglial lineage cells are resident immune cells with a microglial molecular phenotype and ontogeny that exhibit diverse tissue distribution and functions.

