Advancement in Nanotablet Research: An Overview.

Area of Science:

• Nanomedicine
• Materials Science
• Pharmaceutical Sciences

Background:

• Nanotechnology integration revolutionizes drug delivery systems.
• Nanotablets offer a promising frontier for enhanced therapeutic applications.
• Modern technologies are crucial for developing affordable, eco-friendly products.

Purpose of the Study:

• To review the synthesis and characterization of nanotablet drug formulations.
• To explore the potential of nanotablets in various applications, including disease treatment.
• To evaluate nanotablet properties for improved drug delivery.

Main Methods:

• Synthesis and characterization of nanotablets.
• Utilizing techniques like X-ray diffraction, electron microscopy, and physisorption analysis.
• Evaluating pre- and post-compression properties such as hardness and flow.

Main Results:

• Developed innovative nanotablet formulations, including Sophora Alopecuroides nanotablets for cancer treatment.
• Nanotablets demonstrated good hardness and flow properties.
• Sublingual sufentanil nanotablets (Zalviso®) showed efficacy in pain management.

Conclusions:

• Nanotablet synthesis presents a novel and promising approach for diverse applications.
• Nanotablet formulations offer potential for enhanced bioavailability and sustained drug release.
• Further research is warranted based on the promising results of nanotablet development.