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Published on: November 21, 2017
Five new phenolics from the red resin of Dracaena cochinchinensis
Hong Shi1,2, Nan-Pu Lin2, Yong-Xian Cheng1,2
1School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu611137, China.
Abstract:
Five undescribed phenolics including three new flavonoids (1-3), one new flavone glycoside (4) and one neolignan (5), together with seven known compounds were isolated from the resins of Dracaena cochinchinensis (Chinese dragon's blood). Their structures were elucidated based on detailed spectroscopic analysis, including 1D, 2D NMR, mass spectrometry, and electronic circular dichroism (ECD) data analysis. In addition, biological evaluation of compounds 1-5 on anti-renal fibrotic activities were conducted, and the results showed that compounds 1a, 2, and 5 display anti-renal fibrotic activities in TFG-β induced NRK-52e cells.
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