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Updated: May 16, 2025

Quantification of Fungal Colonization, Sporogenesis, and Production of Mycotoxins Using Kernel Bioassays
Published on: April 23, 2012
Neuroprotective furanones from a soil-derived fungus Penicillium paxilli ga254
Guang Li1, Ya-Jing Wang2, Si-Qian Zhou3
1Department of Medicine, Yueyang Vocational and Technical College, Yueyang 414000, China.
Abstract:
Three furanone derivatives (1-3), including one new compound, penicifuranone A (1), and one new natural product (2), along with one known dihydropyranone (4) were isolated from the solid rice medium fermentation of Penicillium paxilli ga254. The structures of these compounds were elucidated using comprehensive NMR spectroscopic analysis. This study represents the first report of these furanone derivatives from this fungus. Additionally, the neuroprotective effects of these compounds against oxygen-glucose deprivation/reperfusion injury in pheochromocytoma-12 cells were investigated.

