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Related Concept Videos

Clinical Trials01:16

Clinical Trials

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Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
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Updated: May 19, 2025

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
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Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

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Hearing Aid Service Models, Technology, and Patient Outcomes: A Randomized Clinical Trial.

Yu-Hsiang Wu1, Elizabeth Stangl1, Kjersten Branscome2

  • 1Department of Communication Sciences and Disorders, University of Iowa, Iowa City.

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|May 15, 2025
PubMed
Summary
This summary is machine-generated.

Audiologist-fitted hearing aids (HAs) provided better outcomes than over-the-counter (OTC) options. However, both OTC and hybrid OTC+ models showed positive results, and HA technology level did not significantly impact outcomes.

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Area of Science:

  • Audiology
  • Health Services Research
  • Medical Devices

Background:

  • Hearing aid (HA) affordability is a barrier to adoption.
  • Higher-cost HAs fitted by audiologists (AUD) and high-end devices are expected to yield better outcomes than over-the-counter (OTC) options.

Purpose of the Study:

  • To compare patient outcomes across different HA service models (AUD, OTC+, OTC) and technology levels (high-end, low-end).

Main Methods:

  • A randomized clinical trial involving 245 adults over 55 with mild to moderate hearing loss and no prior HA experience.
  • Participants were assigned to 1 of 6 groups (3 service models x 2 technology levels).
  • Outcomes were measured using the ecological momentary assessment version of the Glasgow Hearing Aid Benefit Profile (EMA-GHABP).

Main Results:

  • Audiologist-fitted HAs (AUD) showed significantly better outcomes than OTC+ and OTC models.
  • The OTC+ and OTC models demonstrated positive patient outcomes, with no significant difference between them.
  • No significant difference in outcomes was found between high-end and low-end HAs.

Conclusions:

  • While AUD service models yield superior hearing aid benefits, OTC and OTC+ models offer effective and positive outcomes for individuals with mild to moderate hearing loss.
  • The study did not find evidence to support the higher cost of high-end hearing aids, as technology level did not influence outcomes.