Rate and Rationale for Vitrectomy after Pneumatic Retinopexy
Bradley T Smith1, M Zia Siddiqui1, Gautam Vangipuram2
1The Retina Institute of St. Louis, St. Louis, Missouri.
Ophthalmology. Retina
|May 15, 2025
Summary
Nearly 10% of eyes treated for retinal detachment (RD) with pneumatic retinopexy (PnR) required a subsequent vitrectomy for non-RD reasons. Visual acuity outcomes were comparable to eyes needing surgical repair for RD.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Public Health
Background:
- Pneumatic retinopexy (PnR) is a common surgical technique for retinal detachment (RD) repair.
- Pars plana vitrectomy (PPV) is another surgical option for RD and other retinal conditions.
- Understanding the rate and reasons for PPV after PnR is crucial for patient counseling and surgical planning.
Purpose of the Study:
- To determine the incidence of pars plana vitrectomy (PPV) after pneumatic retinopexy (PnR) for retinal detachment (RD) repair.
- To identify the indications for non-RD PPV following PnR.
- To compare visual acuity (VA) outcomes between eyes undergoing non-RD PPV and other management strategies.
Main Methods:
- Retrospective, nonrandomized comparative study using the IRIS® Registry (04/01/2013 to 12/31/2021).
- Inclusion/exclusion criteria applied via billing codes to define three groups: Group 1 (non-RD PPV post-PnR), Group 2 (no surgery post-PnR), Group 3 (RD requiring surgical repair post-PnR).
- Analysis of subsequent PPV indications, follow-up duration, and visual acuity (VA).
Main Results:
- 9,107 eyes were analyzed; 9.4% (556 eyes) required a non-RD PPV after PnR reattachment.
- Common indications for non-RD PPV included internal limiting membrane (25.7%) and epiretinal membrane removal (18.3%).
- Final VA was similar to eyes requiring surgical RD repair (Group 3) but lower than eyes not needing further surgery (Group 2); follow-up was longer than both groups.
Conclusions:
- Approximately 1 in 10 eyes treated with PnR for RD may necessitate a subsequent non-RD PPV.
- Visual outcomes after non-RD PPV are comparable to those requiring surgical RD repair.
- The potential need for PPV should be discussed during patient counseling for PnR.


