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Bone marrow aspirate concentrate adjunct for acetabular labral tear repair: a systematic review and meta-analysis
Seth Spicer1,2, Hanna Brancaccio1,2, Ashley Sundin3
1Department of Medicine, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.
Background:
The objective of this study was to determine the effect of bone marrow aspirate concentrate (BMAC) on long-term patient outcomes when used as an adjuvant to acetabular repair of the labrum.
Methods:
A systematic review and meta-analysis were completed following PRISMA 2020 guidelines. Included in the analysis were controlled studies which assessed functional outcomes via the International Hip Outcome Tool-33 (iHOT-33) 12 or 24 months after acetabular repair with BMAC adjunct. 4 studies totaling 315 participants were analysed.
Results:
Pooled effect sizes for iHOT-33 scores were not significantly different between control and treatment groups at 12 (p = 0.14, Cohen's D ≏ 0.79) or 24 months (p = 0.30, Cohen's D ≏ 0.56).
Conclusions:
Non-significant trends in favour of BMAC augmentation were found in this study. However, the trends reported are promising and warrant further investigation with further randomised controlled trials.
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