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Dietary Riboflavin Intake and the Risk of Stroke: Insights From NHANES 2007-2018
1Department of Neurology Wenzhou Central Hospital Wenzhou China.
Higher dietary riboflavin intake is associated with a reduced risk of stroke in US adults. This study found an inverse relationship, suggesting riboflavin may play a protective role against stroke incidence.
Area of Science:
- Nutrition Science
- Epidemiology
- Cardiovascular Health
Background:
- Limited research exists on the link between dietary riboflavin (vitamin B2) and stroke risk.
- Understanding nutritional factors influencing stroke is crucial for public health.
Purpose of the Study:
- To investigate the prevalence of stroke in the US population.
- To examine the association between dietary riboflavin intake and stroke risk.
Main Methods:
- Cross-sectional study using National Health and Nutrition Examination Survey (NHANES) data (2007-2018).
- Data collected via questionnaires and 24-hour dietary recall.
- Statistical analyses included multivariate logistic regression and restricted cubic splines.
Main Results:
- Stroke incidence was 3.67% among 20,776 participants.
- Increased dietary riboflavin intake was significantly associated with a lower risk of stroke (OR=0.57; 95% CI: 0.38-0.85 for highest vs. lowest intake).
- An L-shaped relationship was observed, with an inflection point around 4.95 mg/day.
Conclusions:
- Higher dietary riboflavin consumption is linked to decreased stroke risk in the US.
- Findings suggest an inverse correlation between riboflavin intake and stroke risk.
- Further research is needed to confirm causality and explore mechanisms.
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