Clinical analysis of 126 cases of stillbirth in high-altitude areas

This study aims to analyze the clinical characteristics of stillbirths in high-altitude areas, strengthen monitoring of high-risk pregnant women, improve maternal health care levels, and reduce perinatal mortality rates.

A retrospective collection of 126 cases of stillbirth in Nyingchi People's Hospital from 2015 to 2021 was divided into an pre-stage group (2015-2019,87 cases) and a post-stage group (2020-2021,39 cases). The incidence of stillbirth and clinical characteristics were compared between the two groups. The cases were classified into maternal factors, fetal factors, placenta/membrane/umbilical cord factors, and unknown causes, and the clinical characteristics and possible etiologies of different gestational ages and antenatal examination situations were analyzed.

The overall incidence of stillbirth in the high-altitude area of this study was 2.36%, with2.07% in the pre-stage group and 3.43% in the post-stage group. There were significant differences between the two groups in gestational age and antenatal examination situation (P = 0.003 and 0.008). The main causes of stillbirth were maternal factors (45.28%), followed by placenta/membrane and umbilical cord factors (28.30%), unknown causes (17.61%), and fetal factors (8.81%). The main causes of stillbirth include hypertensive disorder complicating pregnancy, premature rupture of membranes, severe anemia, and fetal malformatiohypertensive disorder complicating pregnancyns.

This study provides new insights into the prevention and management of stillbirths in high-altitude areas, particularly in terms of maternal factors such as gestational hypertension and severe anemia, by analyzing the clinical characteristics and influencing factors of 126 cases of stillbirths in high-altitude areas. Therefore, this study suggests strengthening prenatal and antenatal health care management to reduce the risk of stillbirth, improve pregnancy outcomes, and promote maternal and child health.