Myopia Control Efficacy of Spectacle Lenses with Dual-Index Aspherical Lenslets: A 1-Year Randomized Clinical Trial

Area of Science:

• Ophthalmology
• Optometry
• Pediatric Eye Care

Background:

• Myopia, a common refractive error, is increasing globally.
• Axial elongation is a key indicator of myopia progression.
• Effective myopia control strategies are crucial for preventing high myopia and associated complications.

Purpose of the Study:

• To evaluate the efficacy of new Dual-Index Aspherical Lenslets (DIAL) spectacle lenses in controlling myopia progression.
• To compare the axial elongation in children wearing DIAL lenses versus single-vision lenses (SVLs) over a 1-year period.

Main Methods:

• A prospective, randomized, double-masked clinical trial involving 80 children aged 8-13 years with myopia.
• Participants were randomized to wear either DIAL or SVL spectacle lenses.
• Axial length (AL) and refractive error were measured at baseline and 6-month intervals over 1 year.

Main Results:

• DIAL lenses significantly reduced axial elongation compared to SVLs (mean difference of -0.18 mm, P < 0.001).
• A significant reduction in spherical equivalent refraction (SER) change was observed with DIAL lenses (mean difference of 0.26 D, P = 0.01).
• The myopia control effect was more pronounced in younger children (8 to <11 years) within the DIAL group.

Conclusions:

• Dual-Index Aspherical Lenslets (DIAL) spectacle lenses demonstrate significant myopia control efficacy in children aged 8-13 years.
• DIAL lenses offer a promising alternative to SVLs for managing myopia progression.
• The study highlights the potential of DIAL lenses, particularly for younger children requiring myopia intervention.