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The New Paradigm of Simulation-Free Radiation Therapy: Practical Recommendations for Successful Clinical
Stephanie Roderick1, Shelley Wong1, Alannah Kejda1
1Department of Radiation Oncology Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
Abstract:
Simulation-free radiation therapy (SFRT) is an emerging patient-centered paradigm for palliative radiation therapy. Feasibility and clinical benefits have been demonstrated by several groups; however, guidance to overcome technical barriers to adoption is limited. This report describes practical recommendations for offline preliminary studies, patient selection, image selection and formatting, planning and treatment considerations, and quality control. These suggestions aim to enable safe, scalable, and effective clinical implementation of SFRT.

