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Related Experiment Video

Updated: May 21, 2025

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

Autoimmune Retinopathy in a Patient with Common Variable Immunodeficiency.

Chiara Muzio^1,2, Giuseppe Casalino², Chiara Mapelli²

¹Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Ocular Immunology and Inflammation

|May 20, 2025

Summary

This case report details a patient with common variable immunodeficiency (CVID) who developed autoimmune retinopathy (AIR). Multimodal imaging revealed retinal lesions, suggesting a link between CVID and immune-mediated eye disease.

Area of Science:

Ophthalmology
Immunology
Medical Imaging

Background:

Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by hypogammaglobulinemia.

Keywords:

Autoimmune retinopathy (AIR)acute zonal occult outer retinopathy (AZOOR)common variable immunodeficiency immune dysregulation multimodal retinal imaging

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Ocular manifestations in CVID are uncommon but can significantly impact vision.

Autoimmune retinopathy (AIR) is a rare condition involving immune-mediated damage to the retina.