Successful management of malignant hyperthermia without dantrolene: A case report
Cailing Zhang1, Huanbin Wang1, Zhi Chen2
1Department of Anesthesiology, Meizhou Traditional Chinese Medicine Hospital (Meizhou Hospital of Guangzhou University of Chinese Medicine), China.
None:
Malignant hyperthermia during surgery represents a significant challenge for anesthesiologists due to its high mortality rate and the risk of long-term physiological damage. Despite preventive measures, malignant hyperthermia cases continue to be reported. The standard and effective response involves the prompt administration of dantrolene, a specific antidote. However, dantrolene availability can differ across countries and regions; not all healthcare facilities can guarantee its immediate availability for early intervention. This case report details the successful management of malignant hyperthermia in an adult during surgery without the use of dantrolene.
Related Concept Videos
Skeletal Muscle Relaxants: Therapeutic Uses
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions
Although all competitive neuromuscular blockers are designed...
Depolarizing Blockers: Pharmocokinetics


