Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ziegler–Natta Chain-Growth Polymerization: Overview01:17

Ziegler–Natta Chain-Growth Polymerization: Overview

3.2K
Ziegler–Natta polymerization is another form of addition or chain‐growth polymerization used for synthesizing linear polymers over branched polymers. The catalyst used for polymerization is the Ziegler–Natta catalyst, named after Karl Ziegler and Giulio Natta, who developed it in 1953. This catalyst is an organometallic complex of titanium tetrachloride and triethyl aluminum, with the active form of the catalyst being an alkyl titanium compound. Using the Ziegler–Natta...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced Delivery of Antimicrobial Peptide via Dual-Functionalized Silica Nanoparticles Achieves Efficient Staphylococcus aureus Biofilm Eradication.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same author

<i>In Silico</i> and <i>in Vitro</i> Selection Method of Peptide Substrates for Protease Selectivity.

ACS biomaterials science & engineering·2025
Same author

Characterising supramolecular gels: general discussion.

Faraday discussions·2025
Same author

Using supramolecular gels: general discussion.

Faraday discussions·2025
Same author

Establishing the Principles for Antithrombogenic Coatings Based on Sol-Gel Films.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Tailoring Peptide Coacervates for Advanced Biotechnological Applications: Enhancing Control, Encapsulation, and Antioxidant Properties.

ACS applied materials & interfaces·2025

Related Experiment Video

Updated: May 22, 2025

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
13:42

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

29.3K

Silylated peptides as building blocks for material synthesis using sol-gel polymerization.

Mehmet B Karakaplan1,2, Vinay S Tiwari1, Omer Agazani1

  • 1Institute of Chemistry and The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. meital.reches@mail.huji.ac.il.

Faraday Discussions
|May 20, 2025
PubMed
Summary

Researchers combined self-assembly and sol-gel synthesis to create novel materials. This bottom-up approach successfully programmed material shape and structure using peptides, offering a versatile method for new material generation.

More Related Videos

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.1K
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

7.2K

Related Experiment Videos

Last Updated: May 22, 2025

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
13:42

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

29.3K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.1K
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
09:54

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

Published on: August 20, 2018

7.2K

Area of Science:

  • Materials Science
  • Biomaterials Engineering
  • Nanotechnology

Background:

  • Bottom-up approaches utilize simple building blocks for material design.
  • Self-assembly (non-covalent interactions) and sol-gel synthesis (covalent bonding) are mild bottom-up methods.
  • Peptides can serve as templates for material synthesis.

Purpose of the Study:

  • To combine self-assembly and sol-gel synthesis for programmed material fabrication.
  • To use self-assembled peptides (Phe-Phe and fluorinated Phe(4-F)-Phe(4-F)) as templates.
  • To investigate the resulting material morphology and structure.

Main Methods:

  • Silylation of self-assembled peptides to enable self-mineralization.
  • Utilizing scanning electron microscopy (SEM) and atomic force microscopy (AFM) for morphological analysis.
  • Employing Fourier transform infrared spectrometry (FTIR) to analyze secondary structure and chemical bonds.

Main Results:

  • Silylated Phe-Phe formed rod-shaped structures.
  • Fluorinated Phe(4-F)-Phe(4-F) formed spherical particles.
  • Structures ranged from nano to micron scale, with evidence of parallel β-sheet and siloxane bonds.

Conclusions:

  • The combined self-assembly and sol-gel approach effectively programs material shape and structure.
  • This method is adaptable for various self-assembled peptides.
  • It presents a versatile bottom-up strategy for novel biomaterial development.