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Updated: May 22, 2025

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Rapid Access to an Enantioenriched Spiro Bisindole Directly from Indole and Acetone

Jing-Yi Wang1, Jie Lin1, Chaoshen Zhang1

  • 1Department of Chemistry and the Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration & Reconstruction, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, 999077, Hong Kong SAR (China).

Angewandte Chemie (International Ed. in English)
|May 20, 2025
PubMed

Keywords:
Asymmetric synthesisChiralityEnantioselectivityIndolesSpirocyclic compounds

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