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Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

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Published on: September 27, 2017

Preferences in atopic dermatitis: A systematic review.

E H Pinborg¹, S B Laursen¹, D Thein¹

¹Department of Dermatology, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.

Journal of the European Academy of Dermatology and Venereology : JEADV

|May 21, 2025

Summary

Industry funding may bias patient and provider preferences for atopic dermatitis (AD) treatments. Efficacy is prioritized in pharma-sponsored studies, potentially influencing treatment decisions.

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Area of Science:

Dermatology
Health Services Research
Pharmaceutical Science

Background:

Recent approvals of novel atopic dermatitis (AD) treatments necessitate understanding patient and provider preferences.
Potential bias in published preference data due to industry funding requires investigation.

Approach:

A descriptive systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Searched PubMed and EMBASE for studies reporting on AD patient, caregiver, and healthcare provider preferences.
Included 42 studies with 19,839 participants, comparing pharma-sponsored and non-pharma-sponsored research.

Key Points:

Pharma-sponsored studies (19) were more recent, had larger populations, and emphasized efficacy, aligning with patient priorities.
Patients in pharma-sponsored studies showed higher willingness to accept side effect risks for other treatment goals.
Non-pharma-sponsored studies more frequently evaluated preferred topical treatment attributes.

Conclusions:

Preference research in atopic dermatitis may be subject to industry bias.
Healthcare providers should exercise caution when using treatment preference data for clinical decision-making.