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Updated: May 23, 2025
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An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
Published on: May 24, 2024
Multivalent FAPI-based radiopharmaceuticals in PET/CT: from cancer diagnostics to theranostics
Taoqian Zhao1, Steven H Liang1
1Department of Radiology and Imaging Sciences, Emory University Atlanta, Georgia 30322, United States.
Abstract:
Radiopharmaceuticals targeting fibroblast activation protein (FAP) have rapidly emerged as innovative agents for cancer imaging and therapy. By selectively binding to cancer-associated fibroblasts (CAFs), radiolabeled FAP inhibitors (FAPIs) enable high-contrast PET/CT imaging across diverse tumor types. This article highlights recent advances in FAPI PET/CT imaging, with particular focus on the influence of multivalency effect in radiotracer development.
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