Neuroretinitis: Diagnostic Associations and Management Approach

Area of Science:

• Ophthalmology
• Retinal Diseases
• Neuro-ophthalmology

Background:

• Neuroretinitis is an inflammatory condition affecting the optic nerve and retina.
• Etiologies of neuroretinitis vary, impacting clinical presentation and prognosis.

Purpose of the Study:

• To detail the clinical presentation, management strategies, visual outcomes, and prognosis of neuroretinitis.
• To analyze a cohort of patients with neuroretinitis across diverse etiologies.

Main Methods:

• Retrospective review of medical records for 10 neuroretinitis patients (12 eyes) from 2014 to March 2024.
• Data collection included clinical features, treatments administered, and follow-up outcomes.

Main Results:

• The cohort included patients with Behcet's disease (6), ocular cat-scratch disease (1), ocular toxoplasmosis (1), and idiopathic neuroretinitis (2).
• Visual acuity improved significantly from presentation (LogMAR 0.4) to last follow-up (LogMAR 0.1).
• Behcet's disease patients experienced recurrent neuroretinitis, necessitating modified treatment regimens.

Conclusions:

• Accurate diagnosis is crucial for effective neuroretinitis management.
• Early initiation of TNF-alpha inhibitors is recommended for neuroretinitis associated with Behcet's disease to enhance control and prevent recurrence.