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Updated: May 23, 2025

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
Catecholaminergic Polymorphic Ventricular Tachycardia in a 16-year-old: Case Report
John Wahhab1, Ani Oganesyan1, Krishi Korrapati1
1Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, Illinois.
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare genetic heart condition. Early diagnosis and management, including implantable cardioverter-defibrillators, are crucial for preventing life-threatening arrhythmias in affected children and young adults.
Area of Science:
- Pediatric Cardiology
- Clinical Genetics
- Electrophysiology
Background:
- Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare, inheritable cardiac disorder.
- It presents with stress- or exercise-induced syncope or cardiac arrest in young individuals.
- Delayed diagnosis is common due to variable symptoms and normal initial tests, leading to high mortality.
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