Where will science take assisted reproduction?

This month's Views and Reviews opens a window to the future. What lies on the horizon for assisted reproduction and gamete/embryo biology? We focus on in vitro gametogenesis and germline editing. Czukiewska et al. reviewed the current state of the science of female germ cell development. This well-supported section recognizes the progress made and the unique aspect of oogenesis that makes full maturation and reproductive capacity difficult. Amato et al. addressed germline editing and the potential capacity to prevent transmission of monogenic diseases with significant morbidity and mortality that currently have no effective treatments. Finally, Cohen and Adashi addressed critical ethical and legal issues surrounding these developing technologies. What does the future hold, and how do we best assure ourselves that we are prepared to wisely introduce these new technologies when they become available?