Related Experiment Video
Updated: Jun 15, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Prevalence of Maternal Depressive Symptoms in Canada during the COVID-19 Pandemic
Heidi Sze Lok Fan1, Stephanie Masina1, Rishma Chooniedass1
1School of Nursing, Faculty of Health and Social Development, University of British Columbia, Kelowna, BC.
Objectives:
This study aimed to assess the prevalence of depressive symptoms among persons who gave birth in Canada during the COVID-19 pandemic, and to identify the factors associated with these symptoms.
Methods:
A cross-sectional survey was conducted between February and April 2021 across Canada. Persons who gave birth during the COVID-19 pandemic were recruited through social media sites and completed an online survey. Depressive symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS).
Results:
The survey was initiated by 4828 persons, and 3817 participants were included in the analysis. The mean EPDS score was 10.41 (SD = 5.66). Almost one-half (47.5%) of the participants showed a high level of depressive symptoms (EPDS ≥11). Participants in Atlantic (52.5%) and Eastern (51.2%) Canada were more likely to have depressive symptoms compared with those in the Prairie region (45.2%) and Western Canada (41.2%) (P < 0.001). The risk of depressive symptoms was higher among participants who gave birth earlier in the pandemic and among those who were more socioeconomically disadvantaged.
Conclusions:
This study shows that a substantial proportion of participants had high levels of depressive symptoms and that participants with older infants and those living in Atlantic and Eastern Canada had higher mean EPDS scores. Assessment of maternal mental health is important during times of societal disruptions such as pandemics. Proactive mental health assessment and support should be provided to all postpartum persons, especially those with lower socioeconomic and educational resources.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview
Depressive Disorders: MDD and Dysthymia
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Disorders of the Female Reproductive System
Panic Disorder

