Related Experiment Video

Updated: Aug 12, 2026

An Ex Vivo Laser-induced Spinal Cord Injury Model to Assess Mechanisms of Axonal Degeneration in Real-time
11:18

An Ex Vivo Laser-induced Spinal Cord Injury Model to Assess Mechanisms of Axonal Degeneration in Real-time

Published on: November 25, 2014

[Effect of lithium salts on neuropathological syndromes of spinal origin]

V N Grafova, E I Danilova

    Biulleten' Eksperimental'Noi Biologii I Meditsiny
    |September 1, 1985
    PubMed

    More Related Videos

    Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells12:55

    Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells

    Published on: October 10, 2017

    Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats08:46

    Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats

    Published on: March 24, 2020

    Related Concept Videos

    Long-term Potentiation01:35

    Long-term Potentiation

    Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
    Long-term Depression01:05

    Long-term Depression

    Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
    Long-term Potentiation01:25

    Long-term Potentiation

    Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
    Hebbian LTP
    LTP can occur when presynaptic neurons...
    Long-term Depression01:03

    Long-term Depression

    Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
    Calcium Ion Concentration Mechanism
    If over time, all...
    Local Anesthetics: Mechanism of Action01:23

    Local Anesthetics: Mechanism of Action

    Local anesthetics (LAs) block sensory and motor impulses by inhibiting the sodium channels on the nerve cell membranes. This induces temporary loss of sensation, relieving pain in a specific body area.
    Local anesthetics are amphiphilic molecules consisting of a hydrophobic aromatic part linked to a hydrophilic group by an ester or amide linkage. They are weak bases and are usually available as salts, which increases their solubility and stability. Once administered, LAs exist in the body either...
    Secondary Spinal Cord Injury llI: Pathophysiology01:25

    Secondary Spinal Cord Injury llI: Pathophysiology

    Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...