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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Taiwan Consensus for the Management of Cardiovascular Risks and Complications in Patients with Prostate Cancer
Wei-Ting Chang1, Jiang-Huang Hong2, Dong-Yi Chen3
1Department of Cardiology, Chi Mei Medical Center, Tainan; School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung.
Prostate cancer treatments can cause cardiovascular disease. Cardio-oncology collaboration is key for personalized care, balancing cancer treatment with heart health to improve patient outcomes.
Area of Science:
- Oncology
- Cardiology
- Cardio-oncology
Background:
- Prostate cancer (PC) is a leading cause of cancer death in men.
- PC frequently coexists with cardiovascular disease (CVD), with rising incidence due to aging populations and increased cancer survival.
- PC treatments like androgen deprivation therapy and chemotherapy can lead to cardiovascular complications such as hypertension and heart failure.
Purpose of the Study:
- To review key issues in managing cardiovascular disease in prostate cancer patients.
- To emphasize the importance of cardio-oncology collaboration for personalized treatment planning and monitoring.
- To highlight the need for balancing cancer control with cardiovascular health.
Main Methods:
- Consensus statement review.
- Discussion of the association between CVD and PC.
- Review of screening, risk assessment, referral criteria, and management strategies for CVD in PC patients.
- Emphasis on multidisciplinary collaboration and patient education.
Main Results:
- PC treatments are associated with significant cardiovascular complications.
- Cardio-oncology collaboration is crucial for optimizing treatment outcomes.
- Personalized treatment plans and close monitoring are essential for managing coexisting PC and CVD.
- Challenges persist in screening and preventive measures.
Conclusions:
- Effective management requires a multidisciplinary approach integrating oncology and cardiology.
- Further research is needed for robust cardiovascular risk assessment tools and preventive strategies.
- Improving interdisciplinary approaches will enhance patient outcomes and reduce cardiovascular morbidity in PC patients.
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