Related Experiment Video
Updated: Mar 18, 2026

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
Published on: May 14, 2016
Dynein: A Multifaceted Therapeutic Target and Its Dysregulation in Aberrant Cell Proliferation
Jivesh Garg1, Laleh Alisaraie1
1School of Pharmacy, Memorial University of Newfoundland, 300 Prince Philip Dr., St. John's, A1B 3V6, Newfoundland, Canada.
None:
This review examines the diverse functions of dyneins, a family of motor proteins involved in intracellular transport processes, the maintenance of cell polarity, and critical signaling pathways essential for cell cycle progression. Dyneins' significant impact on critical cellular functions is mediated through their interactions with an array of organelles, including centrosomes, chromosomes, and endosomes. Dyneins also influence autophagy and immune evasion within the complex environment of cancer. This review underscores the significance of dyneins as an avenue of exploration for comprehending the intricate mechanisms that underpin cancer.
Related Concept Videos
Abnormal Proliferation
Abnormal Proliferation
Inhibition of Cdk Activity
Inhibition of CDK Activity
Mitogens and the Cell Cycle
Negative Regulator Molecules

