Related Experiment Video
Updated: Jan 18, 2026
Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor IRIS
Published on: May 3, 2011
Irisin - a new biomarker for endometrial cancer?
Monika Szarszewska1, Janina Markowska2, Marian Grybos3
1Department of Oncology, Gynaecological Oncology, Poznan University of Medical Sciences, Poznan, Poland. monika.szarszewska@gmail.com.
Objectives:
Irisin is an adipomyokine that has an inhibitory effect on inflammation and possesses anticancer activity. It inhibits cancer cell proliferation, metastasis, and invasion through various signaling pathways associated with carcinogenesis. It has been described to be associated with a number of malignancies in various locations. It has been recognized that it may be a biomarker and prognostic factor in some malignancies. In addition, studies indicate irisin's possible role in treating malignant lesions.
Material And Methods:
In material including 129 cases of endometrial cancer and normal endometrium in a control group of 18 women with uterine myomas.
Results:
There were no statistical differences in irisin protein expression. There were also no differences in irisin expression according to clinical stage, type, and histopathological differentiation.
Conclusions:
Further clinical studies are needed to evaluate irisin activity in endometrial cancer.
More Related Videos
07:54Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Published on: March 25, 2019
08:12Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
Published on: March 14, 2019