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Updated: Sep 20, 2025

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
Gastrointestinal and Nutritional Support, Endocrine, and Hematological Considerations in Sepsis
Arshpal Gill1, Nikolas Touloumes, Justin Dorman
1Author Affiliations: Infectious Diseases and Critical Care Fellow, Divisions of Infectious Disease and Critical Care (Dr Gill), Pulmonary and Critical Care Fellow, Division of Pulmonary and Critical Care (Drs Touloumes, DuMont, Barker, and Malik), Division of Endocrinology (Dr Bononi), Division of Gastroenterology (Dr Gadani), Allegheny Health Network Medicine Institute, Pittsburgh, Pennsylvania; Division of Nursing (Mr Dorman), Allegheny General Hospital, Pittsburgh, Pennsylvania; and Allegheny Health Network, Pittsburgh, Pennsylvania (Ms Flanigan).
None:
The gastrointestinal system alongside nutritional support, the endocrine system, and the hematological system has integral roles in sepsis. Understanding these systems can help clinicians better manage patients with sepsis and potentially improve outcomes. This chapter details these 3 important organ systems and, in particular, the clinical impact on each organ system in sepsis.
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