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Updated: Feb 4, 2026
![An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F66708.jpg&w=3840&q=50)
An Automated Radiosynthesis of [68Ga]Ga-FAPI-46 for Routine Clinical Use
Published on: May 24, 2024
Intracranial and Extracranial Vascular Involvement in Takayasu Arteritis Unresponsive to Multiple Lines of
Srinivas Ananth Kumar1, Madhur Kumar Srivastava1, Kambhampatti Sree Lekha2
1Department of Nuclear Medicine.
Abstract:
Takayasu arteritis (TAK) is a large-vessel vasculitis characterized by granulomatous inflammation of the aorta and its primary branches. The clinical presentation of TAK is heterogeneous. Intracranial vascular involvement in TAK is uncommon and is understudied. Clinical, biochemical, and imaging data always do not correspond, making it difficult to evaluate disease activity in TAK. FAPI PET/CT is a noninvasive whole-body imaging modality that could potentially aid in diagnosis, therapy monitoring, and identifying disease relapse when 18 F-FDG-PET/CT is inconclusive. The authors in this research demonstrate intracranial and extracranial vascular involvement in a patient of TAK on 68 Ga-FAPI-04 PET/CT.
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