Related Experiment Video
Updated: Sep 20, 2025

Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells
Published on: August 20, 2018
Cystatin-mediated enhancement of human epidermal growth factor bioproduction in plants
Hyun Ji Park1, Seung Hee Jo1, Hyoenseo Park1
1Plant Systems Engineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Korea.
Abstract:
Human epidermal growth factor (EGF) fused with the protease inhibitor SlCYS8 and produced in plants showed enhanced stability, yield, and biological activity. This fusion strategy reduced degradation and outperformed commercial EGF in cell-based assays, demonstrating a promising approach for producing stable, functional proteins in plant systems for pharmaceutical applications.
Related Concept Videos
Mitogens and the Cell Cycle
Clinical Applications of Epidermal Stem Cells

