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Updated: Jun 13, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Development of New Indole-Based N-Heterocyclic Carbene Copper Complexes and Their Applications in Catalysis
Chun-Fa Lin1, Ya-Hsuan Tseng1, Hui-Yu Hsieh1
1Department of Chemistry, National Chung Hsing University, Taichung 40227, Taiwan.
Abstract:
This study disclosed the synthesis and characterization of a series of copper N-heterocyclic carbene (NHC) complexes incorporating an indole skeleton. Among these complexes, the Cu-NHC complex with a p-methoxyphenyl group on the indole ring exhibited stability in air for up to six months. In contrast, Cu-NHC complexes bearing alkyl groups on the indole ring were stable under a nitrogen atmosphere for one month. These newly developed Cu-NHC complexes proved effective as catalysts for hydrosilylation of carbonyls in 0.5 mol % loading and N-arylation of oxazolidinones and amides with aryl iodides in 8 mol % loading.
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