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Updated: Jul 31, 2026
11:28
3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening
Published on: October 4, 2017
10.4K
Microgels: from synthesis to tissue regeneration applications.
Sung Yun Hann1,2,3, Yunsung Kang1,3, Haitao Cui4,5
1Department of Precision Mechanical Engineering, Kyungpook National University, Sangju 37224, Republic of Korea.
Biofabrication
|May 28, 2025
Summary
Microgels are versatile hydrogels for tissue engineering and regenerative medicine. Advanced fabrication and 3D bioprinting enhance their use in creating functional tissue constructs and therapies.
Area of Science:
- Biomaterials Science
- Tissue Engineering
- Regenerative Medicine
Background:
- Microgels offer unique properties for mimicking extracellular matrix.
- They are biocompatible, controllable, and injectable hydrogel platforms.
- Their modularity suits diverse tissue engineering needs.
Purpose of the Study:
- To review microgel fabrication methods.
- To highlight microgels' roles in cell encapsulation, therapy delivery, and tissue development.
- To discuss advanced strategies and future potential.
Main Methods:
- Systematic review of microgel fabrication techniques.
- Exploration of advanced strategies like injectable hydrogels and assembled microgel platforms.
- Analysis of 3D bioprinting applications for scaffold generation.
Main Results:
- Advanced strategies enable customizable and functional tissue constructs.
- 3D bioprinting facilitates patient-specific scaffolds with high cellular viability.
- Stimuli-responsive and 4D microgels offer dynamic, tunable microenvironments.
Conclusions:
- Microgels are crucial for developing multifunctional tissue products.
- Efficient mass production and customization are key for clinical translation.
- Innovations will accelerate the integration of microgel-based therapies.
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