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Published on: October 16, 2021
Impact of Pacemaker Implantation on Long-Term Survival After Mitral Valve Surgery
Jessica K Millar1, Callie VanWinkle2, Catherine Wagner3
1Department of Surgery, University of Michigan, Ann Arbor, Michigan; Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Background:
Conduction disorders requiring permanent pacemaker implantation (PPM) after aortic valve surgery have been associated with reduced long-term survival. However, data regarding PPM after mitral valve surgery (MVS) have been limited. We evaluated the impact of new PPM on long-term survival after MVS.
Methods:
All patients who underwent MVS from 2000-2022 at a single institution were stratified by need for a new postoperative PPM. The primary outcome was long-term survival. To evaluate resource use, secondary outcomes included intensive care unit (ICU) length of stay and 30-day hospital readmission. Kaplan-Meier analysis and Cox proportional hazard models were used to assess the association between PPM and long-term survival.
Results:
Among 4690 patients who underwent MVS, 245 (5.2%) required PPM. Patients requiring PPM had more preoperative risk factors, including previous cardiac intervention (47.4% vs 35.3%, P < .01) and concomitant cardiac procedures (89.8% vs 71.42%, P < .01). Patients with PPM had longer ICU lengths of stay (128 hours [interquartile range, 69-194 hours] vs 52 hours [interquartile range, 28-96 hours], P < .01) and more ICU readmissions (19.6% vs 10.8%, P < .01). Kaplan-Meier analysis showed PPM was associated with decreased 10-year survival (P < .01). After adjusting for preoperative risk factors and concomitant operations, PPM was not independently associated with worse long-term survival (hazard ratio, 0.70; 95% CI, 0.40-1.3; P = .28).
Conclusions:
PPM after MVS is not independently associated with worse long-term survival. However, patients requiring PPM have worse clinical status at baseline. These findings demonstrate the importance of identifying patients at risk for PPM to facilitate perioperative planning to improve resource use and survival.
Insights
Permanent pacemaker implantation (PPM) after mitral valve surgery (MVS) is not independently linked to worse long-term survival. Patients needing PPM have higher baseline risk, highlighting the need for proactive perioperative planning.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Devices
Background:
- Conduction disorders after aortic valve surgery requiring permanent pacemaker implantation (PPM) are linked to reduced survival.
- Data on PPM after mitral valve surgery (MVS) are limited, necessitating further investigation.
Purpose of the Study:
- To evaluate the impact of new PPM on long-term survival after MVS.
- To assess resource utilization, including ICU length of stay and 30-day readmission rates.
Main Methods:
- A retrospective analysis of patients undergoing MVS from 2000-2022.
- Stratification based on the need for postoperative PPM.
- Kaplan-Meier analysis and Cox proportional hazard models to assess survival outcomes.
Main Results:
- Of 4690 MVS patients, 5.2% required PPM and had more preoperative risk factors.
- PPM patients experienced longer ICU stays and higher readmission rates.
- While initially associated with decreased survival, PPM was not an independent predictor of worse long-term survival after adjustment.
Conclusions:
- PPM after MVS is not independently associated with diminished long-term survival.
- Patients requiring PPM exhibit a worse baseline clinical status.
- Identifying at-risk patients for PPM is crucial for optimizing perioperative planning, resource use, and survival outcomes.
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