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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Charting the ethical landscape of generative AI-augmented clinical documentation
Qiwei Wilton Sun1, Jennifer Miller2,3, Sarah C Hull3,4
1Yale School of Medicine, New Haven, CT, USA wilton.sun@yale.edu.
Generative artificial intelligence (AI) chatbots offer clinical documentation benefits but raise ethical concerns. Careful implementation, patient notification, and clinician oversight are crucial for responsible AI use in healthcare.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Healthcare
- Clinical Documentation
Background:
- Generative artificial intelligence (AI) chatbots, like ChatGPT, present novel clinical applications.
- Their use in clinical documentation is largely underexplored, despite potential to alleviate administrative burdens.
Purpose of the Study:
- To review the potential applications of generative AI chatbots in clinical documentation (e.g., note-writing, handoffs, prior authorizations).
- To examine the ethical considerations associated with AI-generated clinical documentation.
Main Methods:
- Literature review of generative AI applications in clinical settings.
- Analysis of ethical implications, including bias, patient autonomy, and accountability.
Main Results:
- AI can standardize documentation but may embed biases, impacting vulnerable populations and clinical judgment.
- Potential to transform clinician-patient relationships by reducing administrative tasks and enhancing shared decision-making.
- Algorithmic opacity raises concerns regarding error accountability.
Conclusions:
- Proposes strategies: patient notification, mandatory clinician review, and transparency measures (legislation, error reporting).
- Emphasizes equitable deployment through representative data, stakeholder engagement, cultural sensitivity, and enhanced medical education.
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