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Updated: Sep 20, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Detailed Visualization of the Dissected False Lumen Using Intravascular Ultrasound, Optical Coherence Tomography, and
Takeshi Mori1, Hidekazu Aoyama2, Akimitsu Tanaka1
1Department of Cardiology, Nagoya Tokushukai General Hospital, Kasugai, Aichi, Japan.
Insights
Spontaneous coronary artery dissection (SCAD), a cause of heart attack, was diagnosed in a young man using advanced imaging. Findings suggest a possible link between SCAD and atherosclerosis.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Spontaneous coronary artery dissection (SCAD) is a rare cause of acute myocardial infarction (AMI).
- Diagnosing SCAD solely via coronary angiography (CAG) can be challenging.
- Intravascular imaging is crucial for detailed SCAD assessment.
Purpose of the Study:
- To present a unique case of SCAD diagnosed in a young male patient.
- To highlight the utility of multimodal intravascular imaging in SCAD evaluation.
- To explore potential pathophysiological links between SCAD and atherosclerosis.
Main Methods:
- Coronary angiography (CAG) was performed.
- Intravascular ultrasound (IVUS), optical coherence tomography (OCT), and angioscopy were utilized.
- Detailed imaging of the dissected cavity and lumen was obtained.
Main Results:
- SCAD was confirmed by identifying a false lumen and medial layer disruption.
- Coronary angioscopy revealed mild atherosclerotic lesions.
- This is the first reported case detailing the SCAD dissection entry via angiography.
Conclusions:
- Multimodal intravascular imaging provides unprecedented detail for SCAD diagnosis.
- Findings suggest a potential pathophysiological association between SCAD and atherosclerosis.
- Advanced imaging enhances the understanding of SCAD mechanisms.
Abstract:
Spontaneous coronary artery dissection (SCAD) is a rare but critical cause of acute myocardial infarction (AMI). Diagnosing SCAD solely based on angiographic findings is often challenging; therefore, intravascular imaging modalities such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are often required. Angioscopy allows for direct visualization of the vascular lumen, enabling detailed assessment. Herein, we present a unique case of a young man who presented with AMI. Coronary angiography (CAG) revealed diffuse stenosis in the first septal branch; therefore, IVUS, OCT, and angioscopy were performed to obtain images with unprecedented details to evaluate the dissected cavity. Consequently, SCAD was confirmed owing to the identification of a dissected false lumen and a medial layer disruption. Mild atherosclerotic lesions were observed on coronary angioscopy. SCAD has traditionally been considered unrelated to atherosclerosis; however, our findings may indicate a potential pathophysiological link. This comprehensive imaging approach highlights the potential to improve the understanding of SCAD. This is the first case in which the dissection entry of SCAD was observed in detail using angiography.
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