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Updated: Jun 16, 2025

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Published on: April 10, 2018
Rapid Oxygen Atom Transfer at a Catalysis-Relevant Ni(I)-Alkyl Complex with N2O
Ana Mateos-Calbet1, Paolo Cleto Bruzzese2, Markella Aliki Mermigki1
1Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, Mülheim an der Ruhr 45470, Germany.
None:
To improve our understanding of Ni-catalyzed alcohol formation with N2O, a catalytically relevant Ni(I)-alkyl was synthesized and characterized (EPR, NMR). The complex, prepared via comproportionation and transmetalation, reacted with N2O at ambient temperature within 1 min, producing alcohol and N2. This contrasts sharply with slower reactions of (bpy)NiEt2 (12 h) and catalytic systems (22 h). Theoretical studies suggest a stepwise organometallic Baeyer-Villiger mechanism via a Ni(II)-oxyl intermediate. The high reactivity of Ni(I)-alkyl challenges the notion of N2O's inertness, highlighting its potential as a versatile oxidant in synthesis.
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