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Updated: Jan 18, 2026

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
Published on: December 5, 2019
Multifaceted roles of U-box E3 ligases in plant development
H N Karthik1, Sourabh Parmar1, Nilesh D Gawande1
1Department of Biological Sciences and Engineering, Indian Institute of Technology Gandhinagar, Palaj, Gujarat 382355, India.
None:
Post-translational modifications (PTMs) are crucial for providing plants with the metabolic flexibility needed to regulate cellular signaling during development and stress responses. Ubiquitination, a key post-translational modifications, is mediated by E3 ubiquitin ligases, including the plant U-box (PUB) protein family. PUBs have been implicated in diverse processes such as development, self-incompatibility, cell cycle regulation, and stress and immune responses in various plant species. This review highlights the functional diversity of PUBs, exploring their mechanisms of action, classification based on domains, and tissue-specific expression. By synthesizing current knowledge, this review aims to enhance understanding of how PUBs integrate environmental signals with internal regulatory systems to support plant growth and reproduction.
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