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Quantitative X-Ray Imaging of Mouse Bone by Faxitron

Alexandra A Lawton1, Bernard Freudenthal1, Graham R Williams1

  • 1Molecular Endocrinology Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

Methods in Molecular Biology (Clifton, N.J.)
|May 31, 2025
PubMed

Keywords:
Bone mineral contentDigital X-ray analysisFaxitronJoint diseaseSkeletal phenotype analysisSubchondral bone

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X-ray Imaging01:24

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with X-rays, and by 1900, X-ray was widely...