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Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications

Published on: April 30, 2014

Nationwide Database Analysis Shows Proximal Hamstring Repair in Adult Patients Is Associated With Lower Failure and

Sophia J Wang¹, Ryan T Halvorson¹, Joshua Chung¹

¹Department of Orthopedic Surgery, University of California San Francisco, San Francisco, California, U.S.A.

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association

|May 31, 2025

Summary

This summary is machine-generated.

Proximal hamstring repair demonstrates lower reoperation and infection rates compared to reconstruction. This study analyzed 2,813 patients, finding repair to be a safer option for hamstring tears.

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Area of Science:

Orthopedic Surgery
Sports Medicine
Biomechanical Research

Background:

Proximal hamstring tears are increasingly diagnosed.
Surgical interventions like repair and reconstruction aim to restore function.
Comparative data on reoperation and complication rates are crucial for clinical decision-making.

Purpose of the Study:

To compare reoperation and complication rates between proximal hamstring repair and reconstruction.
To evaluate outcomes in a large, nationwide patient sample.

Main Methods:

Retrospective analysis of a nationwide insurance claims database (PearlDiver).
Inclusion of adult patients with proximal hamstring tears undergoing repair (CPT 27385) or reconstruction (CPT 27386).
Minimum 2-year follow-up, comparing reoperation, emergency department (ED) utilization, and major complications (VTE, sciatic nerve injury, deep infection) using Fisher exact test and Kaplan-Meier analysis.

Main Results:

2,813 patients included; 2,656 repair, 157 reconstruction.
Repair group had significantly lower 2-year reoperation rates (2.8% vs 5.7%, P = .038).
Repair group showed lower infection rates (0.69% vs 4.55%, P < .001) but similar VTE and sciatic nerve injury rates compared to reconstruction.

Conclusions:

Proximal hamstring repair is associated with lower reoperation rates.
Proximal hamstring repair demonstrates reduced postoperative infection rates compared to reconstruction.
Both procedures had comparable rates of venous thromboembolism and sciatic nerve injury.