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Psychometric properties and reference values of the Patient-Reported Outcomes Measurement Information System
Dorinde L Korteling1, Marjolijn Ketelaar2, Selina Limmen3
1Amsterdam UMC location University of Amsterdam, Emma Children's Hospital, Child and Adolescent Psychiatry & Psychosocial Care, Meibergdreef 9, Amsterdam, The Netherlands; Amsterdam Reproduction and Development, Child development, Amsterdam, The Netherlands; Amsterdam Public Health, Mental health, Amsterdam, The Netherlands; Amsterdam Public Health, Methodology, Amsterdam, The Netherlands.
Insights
The Patient-Reported Outcomes Measurement Information System (PROMIS®) pediatric v2.0 Mobility, Upper Extremity, and Pain Interference measures show good validity and reliability in Dutch children. These PROMIS® tools are efficient for assessing pediatric health outcomes.
Area of Science:
- Pediatric Health Outcomes Measurement
- Psychometrics
- Rehabilitation Science
Background:
- The Patient-Reported Outcomes Measurement Information System (PROMIS®) provides validated measures for health status.
- Assessing pediatric physical function and pain is crucial for effective treatment and management.
- Understanding the psychometric properties of PROMIS® pediatric measures in diverse populations is essential.
Purpose of the Study:
- To evaluate the psychometric properties and establish reference values for PROMIS® pediatric v2.0 Mobility, Upper Extremity, and Pain Interference in the Dutch population.
- To compare the measurement efficiency of PROMIS® item banks, short forms, and computerized adaptive tests (CATs).
- To assess the validity and reliability of these PROMIS® measures for use in children.
Main Methods:
- Children aged 8-18 years from the general and clinical populations completed PROMIS® item banks and legacy instruments.
- Structural validity was assessed using graded response models and item-fit statistics.
- Reliability, construct validity, and differential item functioning were evaluated.
Main Results:
- Structural validity was adequate for all PROMIS® item banks.
- PROMIS® Pain Interference demonstrated good reliability, while Mobility and Upper Extremity scales were reliable in the clinically relevant range.
- Computerized adaptive testing (CAT) proved more efficient than other assessment methods, with sufficient construct validity and no differential item functioning observed.
Conclusions:
- PROMIS® v2.0 pediatric Mobility, Upper Extremity, and Pain Interference item banks exhibit sufficient validity in the Dutch general population.
- These PROMIS® measures demonstrate adequate reliability, particularly in the clinically relevant range for pediatric populations.
- The findings support the use of PROMIS® pediatric measures for assessing physical function and pain in Dutch children.
Objectives:
This study investigated psychometric properties and reference values of the Patient-Reported Outcomes Measurement Information System (PROMIS®) pediatric v2.0 Mobility, Upper Extremity, and Pain Interference item banks, short forms and computerized adaptive tests (CATs) in the Dutch general population, supplemented with a clinical sample to improve low-end item parameter estimates.
Study Design And Setting:
Children (aged 8-18 years) completed PROMIS® item banks and legacy instruments (Pediatric Quality of Life Inventory 4.0 subdomain Physical Health, Numeric Pain Rating Scale). Structural validity of item banks was evaluated by fitting a graded response model and inspecting item-fit statistics. Reliability of item banks, short forms, and post-hoc CATs was expressed as standard error of measurement/theta. To compare measurement efficiency of instruments, relative efficiency was calculated. Construct validity was assessed by correlating item banks with legacy instruments. Differential item functioning between Dutch and US samples was evaluated.
Results:
Seven hundred eighty three children participated: 555 children from the general population and 228 children receiving physical therapy. Structural validity was sufficient for all banks. PROMIS® Pain Interference was reliable at the sample mean (standard error of theta < 0.32) and up to 2 standard deviations in the clinically relevant direction (indicating worse health). PROMIS® Mobility and Upper Extremity scales were reliable in the clinically relevant direction, but less so within the normal range. CAT outperformed other assessment methods in efficiency. Construct validity was sufficient. No items displayed differential item functioning.
Conclusion:
The PROMIS® v2.0 pediatric Mobility, Upper Extremity, and Pain Interference item banks displayed sufficient validity in the Dutch general population and sufficient reliability in the clinically relevant direction.

