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Related Experiment Videos

Reversible "locked-in" syndromes.

G Ebinger, L Huyghens, L Corne

    Intensive Care Medicine
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

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    Young patients with locked-in syndrome due to ventral pontine ischemia can recover well. Aggressive supportive therapy is recommended for these cases, as significant recovery is possible.

    Area of Science:

    • Neurology
    • Neuroscience
    • Ischemic Stroke Research

    Background:

    • Locked-in syndrome (LIS) is a rare neurological condition characterized by complete paralysis and inability to communicate, while consciousness is preserved.
    • Ventral pontine ischemia is a potential cause of LIS, impacting motor pathways in the brainstem.

    Observation:

    • This report details two young patients diagnosed with LIS.
    • Both patients experienced symptoms presumed to stem from ventral pontine ischemia.

    Findings:

    • The first patient achieved a full recovery from quadriplegia and mutism.
    • The second patient had only minor residual effects, including mild dysarthria and spasticity.

    Implications:

    • These cases suggest that LIS, even when severe, may not be irreversible.

    Related Experiment Videos

  • Aggressive and sustained supportive therapy during the acute and subacute phases is crucial and may lead to substantial functional recovery in patients with LIS.