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Integrative approaches to network pharmacology studies in wound healing and bone fracture recovery: A comprehensive
Rizwan Ahamed Najimudeen1, Catherin Amaldoss2, Aarthi Raghu2
1School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India.
Abstract:
This review provides a comprehensive exploration of the intricate processes involved in wound healing and bone fracture recovery, delving into the phases and cellular activities that underlie these critical physiological events. The integration of network pharmacology and traditional medicine approaches in the context of wound healing and bone fracture is thoroughly examined, highlighting the potential synergies between modern scientific methodologies and age-old remedies. The Research methodology for network pharmacology studies is meticulously outlined, encompassing data mining, target identification, network construction and analysis, and validation techniques. Various Bioinformatics Databases and tools implied in the network pharmacology are tabulated. The genes responsible for wound healing and bone fracture are also tabulated. By synthesizing knowledge from diverse fields, this review offers valuable insights for advancing therapeutic interventions in wound healing and bone fracture management through network pharmacology study.
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