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Conserved domains and structural motifs that differentiate closely related Rex1 and Rex3 DEDDh exoribonucleases are

Peter W Daniels1, Sophie Kelly1, Iwan J Tebbs1

  • 1School of Biosciences, The University of Sheffield, Sheffield, United Kingdom.

Plos One
|June 2, 2025
PubMed

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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