Effects of Catalyst Bioproducts on In-Office Whitening: A Randomized, Split-mouth Clinical Analysis

Area of Science:

• Dentistry
• Dental Materials
• Cosmetic Dentistry

Background:

• Conventional hydrogen peroxide (H2O2) whitening therapy (CT) involves prolonged application times.
• Optimizing whitening efficacy and patient comfort remains a key goal in cosmetic dentistry.

Purpose of the Study:

• To compare the efficacy and patient-reported outcomes of a novel test therapy (TT) versus conventional therapy (CT) for tooth whitening.
• To evaluate chromatic change, bleaching index, tooth sensitivity, and esthetic self-perception.

Main Methods:

• Thirty patients underwent three whitening sessions, 7 days apart, comparing CT (35% H2O2, 45 min total) with TT (H2O2 gel with peroxidase, 15 min total).
• Objective measures included spectrophotometric analysis of chromatic change (ΔE00) and bleaching index (ΔWID).
• Subjective measures included spontaneous and thermal tooth sensitivity assessments and the Orofacial Esthetics Scale.

Main Results:

• Both therapies achieved similar whitening effects (ΔE00, ΔWID) after the initial session.
• Conventional therapy (CT) resulted in significantly higher intensity and occurrence of spontaneous and thermal tooth sensitivity.
• The test therapy (TT) group reported higher esthetic self-perception (66.6%).

Conclusions:

• The test therapy (TT) offers a comparable tooth whitening effect to conventional therapy (CT).
• TT significantly reduces total treatment time and patient-experienced tooth sensitivity.
• This novel approach enhances patient comfort and esthetic outcomes in dental whitening procedures.