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Pain patterns in intralesional therapy for keloids and hypertrophic scars: A multicenter observational study

Yunyi Liu1,2,3,4,5,6, Zixi Jiang1,2,3,4,5,6, Dan Sun7

  • 1Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

Journal of the European Academy of Dermatology and Venereology : JEADV
|June 3, 2025
PubMed
Abstract

No abstract available in PubMed .

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Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

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