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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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From 0 to 100: Delayed Direct to Implant Breast Reconstruction, an Alternative to Tissue Expansion
Nicole K Le1, Kristen Whalen1, Amra Olafson1
1From the Department of Plastic Surgery, University of South Florida, Tampa, FL.
Annals of Plastic Surgery
|June 3, 2025
Summary
Delayed direct-to-implant (dDTI) breast reconstruction is a safe alternative to tissue expansion (TE) for patients with poor mastectomy flap viability. This method reduces complications and avoids additional surgeries for eligible patients.
Area of Science:
- Plastic Surgery
- Reconstructive Surgery
- Oncology
Background:
- Implant-based breast reconstruction can be challenging with poor mastectomy flap viability.
- Tissue expansion (TE) is a common staged approach, but may require additional procedures.
- Patients may opt to "go flat" before considering delayed reconstruction options.
Purpose of the Study:
- To evaluate the feasibility and outcomes of delayed direct-to-implant (dDTI) reconstruction.
- To compare dDTI with delayed tissue expander (TE) to implant reconstruction.
- To assess complication rates associated with dDTI versus TE.
Main Methods:
- Retrospective study comparing patients undergoing dDTI versus delayed TE reconstruction.
- Included patients who underwent implant placement without tissue expanders after mastectomy.
- Compared outcomes between 33 dDTI breasts and 31 TE breasts.
Main Results:
- dDTI demonstrated significantly fewer complications (3.0%) compared to TE (35.5%) (P < 0.01).
- Logistic regression indicated lower odds of complications with dDTI (OR, 0.06; P < 0.01).
- Average time between mastectomy and dDTI was approximately 279 days.
Conclusions:
- Delayed direct-to-implant reconstruction is a viable and safer alternative to TE.
- dDTI can potentially eliminate the need for additional surgeries and clinic visits.
- This technique offers a beneficial option when initial implant-based reconstruction is not feasible.

