Relationship Between Nail Psoriasis Severity Index and Cardiovascular Risk Assessed by 10 Cardiovascular Risk...

Area of Science:

• Dermatology and Cardiology
• Rheumatology and Public Health

Background:

• Psoriatic arthritis (PsA) is associated with increased cardiovascular risk.
• Nail involvement is common in PsA and may indicate disease severity.

Purpose of the Study:

• To investigate the relationship between nail psoriasis severity and cardiovascular risk in PsA patients.
• To compare cardiovascular risk using multiple established risk calculators.

Main Methods:

• Cross-sectional study of 71 PsA patients (30-75 years old).
• Nail Psoriasis Severity Index (NAPSI) assessed, categorizing patients into groups with (≥1) and without (<1) nail involvement.
• Cardiovascular risk evaluated using 10 calculators, including Framingham (FRS), ACC/AHA ASCVD 2013, SCORE, QRISK3, Reynolds Risk Score (RRS), and PREVENT calculators.

Main Results:

• PsA patients with nail involvement had higher cardiovascular risk scores via SCORE.
• Positive correlations were observed between NAPSI and ACC/AHA ASCVD 2013, FRS BMI, SCORE, PREVENT ASCVD, and PREVENT HF calculators.
• Nail involvement (NAPSI ≥ 1) was linked to elevated cardiovascular risk.

Conclusions:

• A NAPSI score of 1 or higher is associated with increased cardiovascular risk in PsA patients.
• Nail psoriasis severity demonstrates a positive correlation with several cardiovascular risk assessment tools.
• These findings highlight the importance of assessing cardiovascular risk in PsA patients with nail involvement.