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Feasibility of Point-of-Care Urine Self-Testing to Measure Tenofovir Adherence and Predict Viral Suppression
Renata Buccheri1,2, Matthew A Spinelli3, Megan J Heise3
1Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Open Forum Infectious Diseases
|June 4, 2025
Abstract:
This study is the first to demonstrate the feasibility of at-home adherence monitoring using a point-of-care urine assay for tenofovir (TFV). Undetectable TFV is strongly associated with lower viral suppression (odds ratio, 0.19, 95% CI, 0.10-0.34; P < .001), supporting a streamlined, effective approach for monitoring adherence between viral load assessments.

