Related Experiment Video
Updated: Jun 29, 2026

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
Published on: October 1, 2007
Dynamically Tunable Optofluidic Multifocal Microlens Arrays by 3D Printing.
Li Liang1, Jin Du1, Wang Zhang2,3
1Anhui Province Key Laboratory for Control and Applications of Optoelectronic Information Materials, School of Physics and Electronic Information, Key Laboratory of Functional Molecular Solids, Ministry of Education, Anhui Normal University, Wuhu 241003, China.
We developed dynamic multifocal microlens arrays (MLAs) using fluids and optofluidics. These tunable MLAs overcome depth-of-field limitations in 3D imaging, offering adaptable focal planes for enhanced clarity.
Area of Science:
- Optics and Photonics
- Microfluidics
- 3D Imaging Technologies
Background:
- Microlens arrays (MLAs) are crucial for 3D imaging but often have fixed focal lengths, limiting dynamic depth-of-field adjustments.
- Existing multifocal MLAs (MMLAs) made from solid materials struggle to meet dynamic imaging needs.
Purpose of the Study:
- To propose and demonstrate dynamically tunable multifocal MLAs using fluidic materials.
- To overcome the fixed focal length limitations of conventional solid-state MLAs for advanced 3D imaging.
Main Methods:
- Fabrication of a 3D optofluidic chip using two-photon 3D printing.
- Creation of gradient refractive index (RI) distributions within microcavities using miscible liquids.
- Dynamic tuning of optical characteristics by controlling fluid flow rates.
Main Results:
- Demonstrated tunable focal length, numerical aperture, and focal spot intensity via fluidic RI modulation.
- Achieved rapid switching between flat, concave, and multiple-curved focal planes.
- Successfully applied fluidic MLAs to imaging fluorescent microparticles and cells with enhanced magnification and clarity.
Conclusions:
- Fluidic multifocal MLAs offer dynamic tunability and adaptability for large depth-of-field 3D imaging.
- Optofluidic integration provides a novel strategy for overcoming limitations in current 3D imaging systems.
- These tunable MLAs show significant potential for dynamic sample observation and advanced imaging applications.
More Related Videos
06:21Design and Development of a Three-Dimensionally Printed Microscope Mask Alignment Adapter for the Fabrication of Multilayer Microfluidic Devices
Published on: January 25, 2021
07:14Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
Published on: April 11, 2025
Related Concept Videos
Confocal Fluorescence Microscopy
Three-Dimensional Microscopy in Microbiology