Related Experiment Video
Updated: Jun 14, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Electrochemical Decarboxylative Sulfation: A Mild and Efficient Method to Access Organosulfates
Wei Sheng1, Huanhuan Peng1, Chunlan Song1
1State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China.
None:
Sulfation is a crucial transformation in both pathological and physiological processes. However, the conventional synthesis of organosulfates primarily relies on O-sulfonation, which is limited to hydroxyl-containing substrates. Here, we developed a practical and cost-efficient method for electrochemical decarboxylative sulfation. This approach opens new avenues to access organosulfates from readily available carboxylic acids with a broad substrate scope and good functional group compatibility.
Related Concept Videos
Preparation and Reactions of Sulfides
Preparation and Reactions of Thiols
Electrophilic Aromatic Substitution: Sulfonation of Benzene
Phase II Reactions: Sulfation and Conjugation with α-Amino Acids
Structure and Nomenclature of Thiols and Sulfides
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:

